Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jun 21;8(1):e000281. doi: 10.1136/jitc-2019-000281

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Response to treatment with infliximab. Following development of severe inflammatory polyarthritis, elevated CRP at 210 g/L, and the subsequent cessation of nivolumab treatment in April 2017, this patient was commenced on high-dose prednisolone (20–25 mg daily) along with subsequent addition of hydroxychloroquine (200 mg daily, shown in light green) in may 2017 and then MTX (20 mg Weekly shown in green) in August 2017. Following failed attempts to taper prednisolone treatment, arthroscopic synovial biopsy and synovial biopsy-guided therapy with infliximab (shown in dark green) was initiated in quick succession (November 2017 and December 2017, respectively) in addition to holding HCQ. This was followed by a rapid decline in CRP simultaneous with effective tapering of prednisolone therapy. CRP, C reactive protein; HCQ, hydroxychloroquine; MTX, methotrexate.