Table 1.

Distribution of TMED3 Status in Breast Cancer According to Clinicopathologic Characteristics

Characteristics	Number	TMED3 Expression		χ2	P-value
		Negative/Low	High
Breast cancer	182	69	113
Matched normal	60	51	9	40.024	0.000**
Age, years
<60	125	53	72
≥60	57	16	41	3.415	0.065
Tumor size
≤2cm	67	29	38
>2cm	115	40	75	1.300	0.254
ER
Negative	60	16	44
Positive	122	53	69	4.809	0.028*
PR
Negative	72	21	52
Positive	110	49	61	4.625	0.032*
Her2
Negative	129	55	74
Positive	53	14	39	4.199	0.040*
Grade
I	20	9	11
II	107	35	72
III	55	25	30	2.986	0.225
Nodal metastasis
Negative	103	49	54
Positive	79	20	59	9.408	0.002*
TNM stage
I + II	119	41	78
III + IV	63	28	35	1.747	0.186
Triple-negative status
Absent	147	55	92
Present	35	14	21	0.080	0.777
Ki67 index
Low	75	32	43
High	107	37	70	1.225	0.268

Notes: *P<0.05, **P<0.001

Abbreviations: ER, estrogen receptor; PR, progesterone receptor.