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. Author manuscript; available in PMC: 2020 Jun 23.
Published in final edited form as: Thromb Res. 2015 Jul 17;136(3):582–589. doi: 10.1016/j.thromres.2015.07.011

Table 3. SUCRA values and ranking probabilities for VKA, DOAC, and LMWH – Unadjusted and Adjusted Network meta-analysis.

*Adjusted results are from a model with a 10% six-month risk of recurrent VTE in the VKA arm (efficacy), and a 5% six-month risk of major bleeding in the VKA arm (safety). Abbreviations: SUCRA – Surface under the cumulative ranking curve (higher values indicating a potentially better treatment), PrBest – Probability that the respective treatment is the best out of the three compared treatments (caution is warranted in not over-interpreting this measure due to its sensitivity to small and outlying studies), MeanRank - Mean of the distribution of ranking probabilities.

Analysis Treatment Recurrent VTE Major Bleeding

SUCRA PrBest MeanRank SUCRA PrBest MeanRank
Unadjusted NMA VKA 2.6 0.0% 2.9 39.1 9.7% 2.2

DOAC 68.0 41.2% 1.6 84.6 79.0% 1.3

LMWH 79.4 58.7% 1.4 26.2 11.3% 2.5

Adjusted NMA* VKA 20.2 2.5% 2.6 52.0 13.4% 2.0

DOAC 84.5 74.7% 1.3 89.7 84.1% 1.2

LMWH 45.2 22.8% 2.1 8.2 2.5% 2.8