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. 2020 Jun 15;15:1377–1390. doi: 10.2147/COPD.S233398

Table 3.

Management Options That Need to Be Considered for Patients at Risk of Fragility Fractures

Management for “at risk” of fracture group is holistic and includes recommendation of
  • Engaging in discussion and informing the patient appropriately (via conversation and leaflets)

  • Smoking cessation interventions where appropriate. It may be an additional encouragement for some to stop smoking

  • Recommendation to increase activity (especially weight-bearing exercise)

  • Offering referral to pulmonary rehabilitation (if not attended in the last year)

  • Dietary optimisation

  • Falls risk ± falls programme where applicable

  • Frailty assessments ± optimisation where applicable

  • Pharmacological elements:
    • Medicines review
      • Optimising inhaled corticosteroid dose
      • Reviewing and monitor oral corticosteroid rescue courses
      • Keeping any maintenance oral corticosteroids to a minimum
    • Bisphosphonates but bearing in mind
      • Adherence
      • Side effects – especially gastro-oesophageal reflux disease and osteonecrosis.
      • Combined with oral calcium and vitamin D – adequate vitamin D levels prior to initiating bisphosphonates reduce the risk of secondary hyperparathyroidism and increases the effectiveness of anti-resorptive medications
      • Given for a certain duration but then drug holiday usually required
    • Specialist Review required prior to anabolics and intravenous preparations