Table 4.
Genotype Polymorphisms’ Distributions and Allele Frequencies of MIR34B/C in MDD Patients and Healthy Controls
| SNPs | Type | n | Genotyping (%) | χ2 | p-value | Allele (%) | χ2 | p-value | HWE-p | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| rs4938723 | T/T | T/C | C/C | T | C | |||||||
| Cases | 441 | 218(49.4) | 174(39.5) | 49(11.1) | 4.23 | 0.121 | 610(69.2) | 272(30.8) | 3.63 | 0.057 | 0.115 | |
| Controls | 222 | 91(41.0) | 102(45.9) | 29(13.1) | 284(64.0) | 160(36.0) | 0.960 | |||||
| rs2187473 | C/C | C/T | T/T | C | T | |||||||
| Cases | 421 | 263(62.5) | 143(34.0) | 15(3.6) | 4.39 | 0.111 | 669(79.5) | 173(20.5) | 1.74 | 0.187 | 0.408 | |
| Controls | 223 | 155(69.5) | 58(26.0) | 10(4.5) | 368(82.5) | 78(17.5) | 0.140 | |||||
| rs28757623 | G/G | G/C | C/C | G | C | |||||||
| Cases | 442 | 249(56.3) | 163(36.9) | 30 (6.8) | 4.15 | 0.125 | 661(74.8) | 223 (25.2) | 3.55 | 0.060 | 0.637 | |
| Controls | 221 | 106(48.0) | 97(43.9) | 18(8.1) | 309(69.9) | 133(30.1) | 0.520 | |||||