Table 3.
Overall | Low NLRa | High NLRa | |||||
---|---|---|---|---|---|---|---|
N | % | N | % | N | % | P-value | |
Overall | 2701 | 100.0 | 939 | 34.7 | 1762 | 65.2 | -- |
Age, mean (SD) | 68.6 | 10.9 | 67.2 | 11.2 | 69.3 | 10.7 | <.0001 |
Gender | <.0001 | ||||||
Female | 1070 | 39.61 | 421 | 44.83 | 649 | 36.83 | |
Male | 1631 | 60.39 | 518 | 55.17 | 1113 | 63.17 | |
Race | <.0001 | ||||||
Caucasian | 2054 | 76.05 | 668 | 71.14 | 1386 | 78.66 | |
African American | 484 | 17.92 | 199 | 21.19 | 285 | 16.17 | |
Other race | 163 | 6.03 | 72 | 7.67 | 91 | 5.16 | |
Charlson Index, mean (SD) | 2.50 | 1.62 | 2.24 | 1.47 | 2.64 | 1.67 | <.0001 |
Procedure type | <.0001 | ||||||
Endovascular | 1395 | 51.65 | 594 | 63.26 | 801 | 45.46 | |
Open | 1306 | 48.35 | 345 | 36.74 | 961 | 54.54 | |
PAD Severity | <.0001 | ||||||
Claudication | 1384 | 51.24 | 569 | 60.60 | 815 | 46.25 | |
Rest pain | 408 | 15.11 | 133 | 14.16 | 275 | 15.61 | |
Tissue loss | 909 | 33.65 | 237 | 25.24 | 672 | 38.14 | |
NLR, mean (SD) | 6.00 | 4.22 | -- | -- | -- | -- | -- |
Pre-Existing Conditions | |||||||
Chronic heart disease | 1343 | 49.72 | 447 | 47.60 | 896 | 50.85 | .10 |
Chronic kidney disease | 443 | 16.40 | 100 | 10.65 | 343 | 19.47 | <.0001 |
Diabetes | 1120 | 41.47 | 372 | 39.62 | 748 | 42.45 | .15 |
Outcomes | |||||||
Renal failure | 135 | 5.00 | 22 | 2.34 | 113 | 6.41 | <.0001 |
Cardiac/MI | 103 | 3.81 | 29 | 3.09 | 74 | 4.20 | .15 |
Respiratory problems | 135 | 5.00 | 24 | 2.56 | 111 | 6.30 | <.0001 |
Infection | 313 | 11.59 | 66 | 7.03 | 247 | 14.02 | <.0001 |
Amputation | 175 | 6.48 | 26 | 2.77 | 149 | 8.46 | <.0001 |
In-hospital death | 20 | 0.74 | 3 | 0.32 | 17 | 0.96 | .06 |
Length of stay, mean (sd) | 4.25 | 5.42 | 2.70 | 3.34 | 5.08 | 6.09 | <.0001 |
Length of stay > 10 days | 266 | 9.85 | 35 | 3.73 | 231 | 13.11 | <.0001 |
Post-operative NLR Low (< 5.96), High (≥ 5.96).
PAD = peripheral arterial disease; SD = standard deviation; MI = myocardial infarction; NLR = neutrophil-lymphocyte ratio