Figure 5:

In both sexes, mitochondrial respiration was modified by diet, but only by FST exposure in males (three-way ANOVA with diet x stress exposure x measurement). A) In males, acute stress exposure significantly increased oxygen consumption rate (OCR) in comparison to control groups regardless of diet. Regardless of FST experience, fructose-fed males demonstrated significantly lower OCR compared to chow-fed males. B) Acute stress exposure did not affect mitochondrial respiration in females. In the baseline group, fructose-fed females had significantly increased respiration rates compared to chow-fed females. Circles represent mean ± SEM. *p<0.05. Administration of drugs for the Cell Mito Stress Test indicated by text and colored panels.