Table 2.
Outcome | All Patients (N = 78) |
---|---|
Cytokine release syndrome | 66 (85%) |
None | 12 (15%) |
Grade 1 | 28 (36%) |
Grade 2 | 28 (36%) |
Grade 3 | 8 (10%) |
Grade 4 | 2 (3%) |
Neurotoxicity | 52 (67%) |
None | 26 (33%) |
Grade 1 | 17 (22%) |
Grade 2 | 13 (17%) |
Grade 3 | 22 (28%) |
Tocilizumab | 48 (62%) |
Dexamethasone | 38 (49%) |
Response to therapy | |
Remission/positive response | 43 (55%) |
Progression | 28 (36%) |
Unable to gauge response | 3 (4%) |
Death during admission for CAR-T | 4 (5%) |
Abbreviation: CAR-T, chimeric antigen receptor therapy.