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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Curr Opin Chem Biol. 2020 Feb 6;56:63–71. doi: 10.1016/j.cbpa.2020.01.001

Figure 1. The Inforna approach to define druggable RNA targets and small molecules to target them by using human genome sequence and the RNAs that it encodes.

Figure 1.

Features of Inforna include: (i) defining folded RNA structures and compounds to bind them; (ii) the uniqueness of a target site; (iii) the selectivity of the small molecule for a given target; (iv) approaches to increase selectivity and affinity of lead small molecules.