Table 2.
Variables | HR | 95% CI | P |
---|---|---|---|
Age (per 10 years) | 1.04 | 0.99 – 1.09 | 0.091 |
Education (> 12 years) | 0.90 | 0.80 – 1.01 | 0.069 |
Lobar CMBs (per each additional CMB) | 1.88 | 1.13 – 3.12 | 0.015 |
Increasing CSS Severity (None - Focal - Disseminated) | 1.51 | 1.07 – 2.13 | 0.021 |
APOE ε2 or ε4 (≥ 1 copy) | 1.90 | 1.10 – 3.29 | 0.023 |
Results derived from combined analysis of MGH-ICH and ERICH data (n = 230)
Abbreviations: APOE = Apolipoprotein E, CSS = Cortical Superficial Siderosis, CMB = Cerebral Microbleeds, ICH = Intracerebral Hemorrhage, OAT = Oral Anticoagulation Therapy