Table 2.

Adjusted Multilevel Linear Regression for Change in Total Simple 7 Score

	Intervention		Control		Difference between groups
Multiple imputation results	Estimate (95% CI)	p-value	Estimate (95% CI)	p-value	Estimate (95% CI)	p-value
All participants (N=182)
Total Simple 7 score	1.08 (0.63, 1.53)	<0.001	0.05 (−0.35, 0.45)	0.81	1.03 (0.44, 1.61)	<0.001
Participants ≥60 years (N=70)
Total Simple 7 score	1.28 (0.71, 1.86)	<0.001	0.52 (−0.06, 1.11)	0.08	0.75 (−0.04, 1.56)	0.063

Note: Boldface indicates statistical significance (p<0.05). Differences were evaluated using a linear mixed-effects model with multiply imputed data adjusted for education, age, baseline Simple 7 score, and including site as a random effect. Site, baseline age, baseline education, baseline total Simple 7 score, and outcome total Simple 7 score were included in the multiple imputation models. Possible total Simple 7 score ranges from 0 to 14 and ranged from 3 to 12 in this sample. Average baseline total Simple 7 score among the 87 intervention group participants was 7.04 (SD=0.19) and 6.96 (SD=0.18) among the 95 control participants. Among women aged >60 years, mean baseline score in the intervention group was 6.63 (SD=0.32) and 3.36 (SD=0.30) in the control group.