Skip to main content
. Author manuscript; available in PMC: 2021 Jun 20.
Published in final edited form as: Annu Rev Biochem. 2020 Mar 16;89:103–133. doi: 10.1146/annurev-biochem-011520-104722

Figure 1: Sources of DSBs and the responses mediated by DDC kinases.

Figure 1:

DSBs originating from endogenous or exogenous sources trigger the activation of DDC kinases that coordinate an intricate cellular response that includes cell cycle arrest and the mobilization of DSB-repair pathways.