Table 2.

Risk Factors for Overall Mortality and Cancer-Specific Mortality

Variables	Overall Mortality				Cancer-Specific Mortality
	Univariate Cox Regression		Multivariate Cox Regression		Univariate Cox Regression		Multivariate Cox Regression
	HR (95% CI)	p Value	HR (95% CI)	p Value	HR (95% CI)	p Value	HR (95% CI)	p Value
Age at diagnosis (years)	1.008 (0.979–1.038)	0.599	0.988 (0.954–1.023)	0.480	0.998 (0.965–1.033)	0.919	0.973 (0.934–1.014)	0.194
T Category
T1	ref		ref		ref		ref
T2	1.310 (0.691–2.482)	0.408	0.881 (0.443–1.749)	0.716	1.198 (0.571–2.514)	0.633	0.737 (0.333–1.633)	0.452
T3/T4	ND		ND		ND		ND
NA	2.774 (0.824–9.336)	0.099	0.716 (0.142–3.622)	0.686	2.511 (0.574–10.579)	0.221	0.942 (0.154–5.771)	0.949
N Category
pN0	ref		Ref		ref		ref
pN1	2.240 (1.240–8.466)	0.016	3.114 (1.172–8.278)	0.023	5.437 (1.516–19.492)	0.009	5.690 (1.555–20.816)	0.009
pN2/pN3	11.152 (4.389–28.338)	<0.001	8.386 (3.171–22.182)	<0.001	18.021 (5.171–62.798)	<0.001	15.374 (4.186–56.457)	<0.001
NA	16.557 (4.630–59.199)	<0.001	28.684 (5.552–148.200)	<0.001	16.326 (2.712–98.292)	0.002	31.264 (3.561–274.503)	0.002
Adjuvant Therapy
TAM	ref		Ref		ref		ref
X-ray + TAM	0.772 (0.386–1.544)	0.465	0.504 (0.229–1.107)	0.088	0.582 (0.272–1.247)	0.164	0.320 (0.134–0.763)	0.010
X-ray + TAM + LHRH	ND		ND		ND		ND
CXCR4
Low	ref		ref		ref		ref
High	4.646 (2.374–9.093)	<0.001	3.027 (1.480–6.191)	0.002	4.480 (2.059–9.748)	<0.001	2.498 (1.089–7.730)	0.031

CI, confidence interval; HR, hazard ratio; NA, not available; ND, not done; ref, reference.