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. 2020 Jun 23;10:10180. doi: 10.1038/s41598-020-67152-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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CD47 upregulation in mouse intestinal epithelium during DSS-induced experimental colitis. The mice (n = 20) were treated with 2%DSS for various time points. (a) CD47 immunostaining (red) and E-cadherin (green) doubling staining of colonic section in day 0, day 3, day 7, day 10 (n = 5). (b,c) Western blotting analysis of CD47 expression in dissected intestinal epithelium from DSS-treated mice on day 0, day 3, day 6, day 9 and day 12 post-treatment (n = 3). **P < 0.01, ***P < 0.001, ****P < 0.0001 versus day 0.