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. 2020 Jun 23;10:10180. doi: 10.1038/s41598-020-67152-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Intestinal epithelil cell CD47 inhibits cell wound healing and proliferation processes. (a) Overexpression or depletion of CT26 epithelial cells CD47 inhibits or promotes cell wound healing, respectively. (b) EDU assay of proliferation of CT26 cells. Cells were overexpressed or depleted CD47 via transfecting with CD47-expressing vector or CD47 siRNA. *P < 0.05, ***P < 0.001.