Table 3.
Effect of the treatment with GM1-Ptx micelles in the incidence of metastases in tumor-bearing mice.
| Group 1 | Group 2 | Group 3 | Group 4 | Group 5 | |
|---|---|---|---|---|---|
| Control Tumor | Empty GM1 2xweek | GM1-Ptx 15 mg/kg 1/week |
GM1-Ptx 15 mg/kg 2/week |
GM1-Ptx 30 mg/kg 1/week |
|
| Ptx doses (mg/kg/week) | 0 | 0 | 15 | 30 | 30 |
| % of animals with metastases | |||||
| Pulmonary macrometastases | 40 | 56 | 22,2 | 0 | 0 |
| Pumonary. micrometastases | 84 | 100 | 100 | 25 | 100 |
| Hepatic macrometastases | 5 | 33 | 0 | 0 | 0 |
| Renal macrometastases | 0 | 0 | 0 | 0 | 0 |