Table 2.

Estimated trends in sPIKE from state-space models by region and time period. Trends in bold were significant after Bonferroni correction.

Region	Years	Estimate ± SE	t	P
Entire continent	2003–2010	0.03 ± 0.002	13.40	<0.001
	2011–2018	−0.03 ± 0.004	−6.13	<0.001
Central Africa	2003–2010	0.03 ± 0.01	4.42	0.004
	2011–2018	−0.01 ± 0.004	−2.54	0.04
Eastern Africa	2003–2010	0.04 ± 0.01	6.11	0.001
	2011–2018	−0.06 ± 0.01	−6.35	0.001
Southern Africa	2003–2010	0.03 ± 0.006	5.80	0.001
	2011–2018	0.01 ± 0.01	0.64	0.55
West Africa	2003–2010	0.05 ± 0.01	6.89	<0.001
	2011–2018	−0.003 ± 0.01	−0.27	0.80