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. 2020 May 27;42(7):805–815. doi: 10.1007/s13258-020-00932-w

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© The Author(s) 2020

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Fig. 6 — Hierarchical cluster analysis and heat map of the relative synonymous codon usage (RSCU) values of each codon in HBV. Each square in the heat map represents the log ratio of the RSCU value of each codon (in rows) within the HBV genome (in columns). Colors indicate the magnitude of RSCU values: white, RSCU = 1 (no bias in codon usage); blue RSCU < 1; red, RSCU > 1