Table 1.
Examples of grading scales for DR
| ETDRS grading (level) | ICO grading | AAO grading | RCOphth grading |
|---|---|---|---|
| No disease (10) | No abnormalities | No abnormalities | No disease |
| MA only (20) |
Mild NPDR MA only |
Mild NPDR MA only |
Low risk |
| Mild NPDR (35) |
Moderate NPDR MA + other signs, excluding those indicating severe NPDR |
Moderate NPDR MA + other signs, but none defining severe NPDR |
– |
| Moderate NPDR (43) | – | – | High risk |
| Moderately severe NPDR (47) | – | – | – |
| Severe NPDR (53A–D) |
Severe NPDR >20 intraretinal hemorrhages in all quadrants Venous beading in two or more quadrants IRMA in one or more quadrant |
Severe NPDR Intraretinal hemorrhages in all quadrants Venous beading in two or more quadrants IRMA in one or more quadrant |
– |
| Very severe NPDR (53E) | – | – | – |
| Mild PDR (61) |
PDR Neovascularization and/or vitreous/preretinal hemorrhage |
PDR Neovascularization and/or vitreous/preretinal hemorrhage |
PDR |
| Moderate PDR (65) | – | – | – |
| High-risk PDR (71, 75) | – | – | – |
| Advanced PDR (81, 85) | – | – | – |
AAO American Academy of Ophthalmology, DR diabetic retinopathy, ETDRS Early Treatment Diabetic Retinopathy Study, ICO International Council of Ophthalmology, IRMA intraretinal microvascular abnormalities, MA microaneurysms, NPDR non-proliferative diabetic retinopathy, PDR proliferative diabetic retinopathy, RCOphth Royal College of Ophthalmologists