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. 2020 Jun 17;8:287. doi: 10.3389/fpubh.2020.00287

Table 2.

Hematological profiles for patients with primary DENV infections.

Dengue 1 Dengue 2 Dengue 3 Dengue 4
Mean (range) OR (95% CI) Mean (range) OR (95% CI) Mean (range) OR (95% CI) Mean (range) OR (95% CI)
N (%) N (%) N (%) N (%)
AST (IU/L) 228 (59–406) 2.0 (0.19 20.14) 139 (27-570) 0.75 (0.13–4.09) 114 (41–288) 0.83 (0.12–5.47) Sample size too small
6 (86%) 12 (75%) 6 (50%)
ALT (IU/L) 101 (20–247) 1.86 (0.38–8.98) 146 (16–751) 0.83 (0.25–2.72) 83.3 (28–277) 0.75 (0.17–3.29) 86.2 (28–221) 1.0 (0.12–7.81)
5 (62%) 11 (48%) 4 (33%) 1 (16.6%)
TLC (109/L) 41 (12.9–52.7) 1.39 (0.3–6.41) 30 (4–55.5) 0.56 (0.2–1.56) 27.1 (8.2–48.1) 2.89 (0.7–11.87) 15.8 (3.5–24.1) 0.51 (0.07–3.27)
5 (62%) 19 (46%) 9 (75%) 1 (20%)
Platelets (109/L) 46.5 (12-133) 546E+006 119 (19–330) 370E+015 134 (3–258) 0.94 (0.24–3.57) 114 (43–204) 2.0 (0.2–19.09)
8 (100%) 23 (57%) 8 (67%) 4 (80%)
Hemoglobin (gm/dL) 15.4 (12.2–17.2) 7.14E−009 13.5 (9.2–17.4) 1.81 (0.33–9.89) 13.5 (10.5–18.1) 1.43 (0.25–8.18) 13.8 (12.1–14.8) 7.14E−009
0 (0%) 6 (16%) 2 (14%) 0 (0%)
Hematocrit 44.8 (36–48.2) 0.10 0.009–1.09 39.2 (32.7–46.9) 1.04 (0.23–4.7) 37.5 (31.4–42.8) 2.0 (0.18–22.05) 40.2 (36.6–42.6) 629E+006
0 (0%) 10 (62%) 3 (75%) 1 (25%)

These patients were NS1 and RT-PCR positive for only one serotype and negative for DENV neutralizing antibodies via PRNT. Bold font indicates statistical significance. OR, odds ratio; CI, confidence interval; N, number of patients.