Table 3.
Symptoms for patients with primary DENV infections.
Dengue 1 | Dengue 2 | Dengue 3 | Dengue 4 | |
---|---|---|---|---|
OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |
N (%) | N (%) | N (%) | N (%) | |
Arthralgia | 0.0 | 4.0 (0.45–35.35) | 2.34E−009 | 2.33 (0.22–24.4) |
0 | 6 (14.2%) | 0 | 1 (20%) | |
Myalgia | 1.11 (0.25–4.84) | 0.76 (0.28–2.05) | 1.11 (0.31–3.89) | 1.71 (0.26–10.93) |
4 (50%) | 19 (45.2%) | 6 (50%) | 3 (60%) | |
Headache | 0.45 (0.06–2.91) | 1.02 (0.37–2.8) | 0.69 (0.15–3.09) | 6.78 (0.71–64.42) |
2 (25%) | 17 (40.4%) | 4 (33.3%) | 4 (80%) | |
Rash | 0.74 (0.08–6.82) | 0.59 (0.15–2.28) | 1.10 (0.2–5.99) | 4.25 (0.61–29.520 |
1 (12.5%) | 5 (12%) | 2 (16.6%) | 2 (40%) | |
Hemorrhagic manifestations | 1.63 (0.31–10.75) | 1.23 (0.33–4.61) | 0.90 (0.17–4.76) | 6.78E−009 |
2 (25%) | 8 (19%) | 2 (16.6%) | 0 | |
Fever ≥38°C | 0.08 (0.01–0.75) | 1.50 (0.54–4.15) | 0.92 (0.24–3.390 | 618E+006 |
1 (12.5%) | 23 (54.7%) | 6 (50%) | 5 (100%) | |
Nausea/vomiting | 0.62 (0.13–2.89) | 1.32 (0.44–3.92) | 0.75 (0.19–2.86) | 4.3 (0.23–78.63) |
5 (62.5%) | 31 (73.8) | 8 (66.6%) | 4 (80%) | |
Burning micturition | 0.79 (0.08–7.25) | 0.54 (0.13–2.09 | 2.28 (0.49–10.53) | 1.47 (0.14–14.72) |
1 (12.5%) | 5 (12%) | 3 (25%) | 1 (20%) | |
Neurologic symptoms | 2.37E−009 | 3.1 (0.61–15.88) | 1.02 (0.19–5.47) | 6.92E−009 |
0 | 9 (21.4%) | 2 (16.6%) | 0 | |
Dengue fever diagnosis | 1.62 (0.27 to 9.49) | 0.96 (0.33–2.8) | 0.87 (0.22–3.38) | 0.73 (0.08–6.58) |
6 (75%) | 27 (62.4%) | 7 (58.3%) | 3 (60%) | |
Antibiotics prescribed | 0.40 (0.07–2.15) | 1.42 (0.50–4.03) | 1.13 (0.3–4.2) | 0.88 (0.13–5.670 |
2 (25%) | 18 (42.8%) | 5 (41.6%) | 2 (40%) | |
Eye pain | 0.0 | 204E+006 | 6.88E−009 | 0.0 |
0 | 3 (7%) | 0 | 0 | |
Fever ≥38.5°C | 1.83E−009 | 0.91 (0.26–2.19) | 2.78 (0.7–9.1) | 1.55 (0.53–22.76) |
0 | 12 (26.2%) | 6 (50%) | 2 (40%) |
Logistic analysis was performed in which a single serotype was compared against the other serotypes. These patients were NS1 and RT-PCR positive for only one serotype and negative for DENV neutralizing antibodies via PRNT. Bold font indicates statistical significance. OR, odds ratio; CI, confidence interval; N, number of patients.