Table 3.
mtDNA content and blastocyst quality, according to ploidy and oocyte origin
| Blastocyst quality | PGT-A | Oocyte origin | Mean | SD | 95% CI (mean) | n | p value |
|---|---|---|---|---|---|---|---|
| A | Aneuploid | Fresh | 26.8 | 9.8 | (18.5, 35.0) | 8 | 0.083 |
| Vitrified | 19.5 | 2.7 | (16.2, 22.9) | 5 | |||
| Euploid | Fresh | 27.1 | 7.7 | (24.1, 30.1) | 27 | 0.053 | |
| Vitrified | 23.0 | 4.8 | (20.0, 26.1) | 12 | |||
| B | Aneuploid | Fresh | 28.9 | 10.5 | (26.4, 31.3) | 74 | 0.709 |
| Vitrified | 28.2 | 9.8 | (25.5, 30.9) | 52 | |||
| Euploid | Fresh | 28.1 | 9.5 | (25.7, 30.5) | 61 | 0.693 | |
| Vitrified | 27.3 | 10.0 | (24.10, 30.5) | 40 | |||
| C | Aneuploid | Fresh | 33.7 | 12.1 | (12.1, 31.0) | 82 | 0.804 |
| Vitrified | 34.3 | 16.0 | (16.0, 30.5) | 70 | |||
| Euploid | Fresh | 29.2 | 9.8 | (25.6, 32.8) | 31 | 0.817 | |
| Vitrified | 29.8 | 10.3 | (25.7, 33.9) | 27 | |||
| D | Aneuploid | Fresh | 36.0 | 3.1 | (33.9, 38.0) | 11 | 0.854 |
| Vitrified | 37.6 | 10.1 | (− 53.0, 128.3) | 2 | |||
| Euploid | Fresh | - | - | - | - | - | |
| Vitrified | 40.6 | 0.4 | (36.6, 44.5) | 2 |
Mean mtDNA content and 95% CI of aneuploid and euploid blastocysts coming from fresh and vitrified oocytes according to the blastocyst quality
Blastocyst quality: A—excellent; B—good; C—moderate; D—poor
PGT-A, preimplantation genetic testing for aneuploidies; SD, standard deviation; CI, confidence interval; n, number of blastocysts