Table 3.
QD | Model | Administration | QD concentration | Exposure duration | Toxicity | Ref |
---|---|---|---|---|---|---|
InPZnS QDs | Hydra vulgaris | Direct exposure | 70 nM | 72 h | Hydra is very susceptible to aquatic pollutants; these QDs may not represent a concrete risk for environmental health | Allocca et al. 2019 |
Indium-based QDs (CFQD) | Female Lister Hooded rats | IV injection | 12.5 mg/kg and 50 mg/kg | 90 days | QDs mainly accumulated in the liver and spleen and were excreted from the body gradually and possess good biocompatibility | Yaghini et al. 2018 |
InZnP and InZnPS QD | Human skin samples | In vitro | 6.25–200 nM (cytotoxicity and cell proliferation), 12.5–100 nM (oxidative stress) or 50 nM (comet assay, X-ray absorption spectroscopy, electron microscopy) | 24 h | Toxicity of pristine QDs was essentially non-toxic and the toxicity of aged QDs, which proved to be all toxic | Tarantini et al. 2019 |