Table 4.
QD | Model | Administration | QD concentration | Exposure duration | Toxicity | Ref |
---|---|---|---|---|---|---|
Ag2S QD | Chinese hamster lung fibroblast (V79) | In vitro | 5–2000 μg/mL | 24 h | The cytotoxic effects of DMSA/Ag2 S QDs may occur at high doses through the apoptotic pathways | Vardar et al. 2019 |
PEGylated CuInS2/ZnS | Male BALB/c mice of 7 weeks old | IV injection | 100 μL | 90 days | No significant difference in body weight, no histopathological and no biochemical abnormalities | Zou et al. 2019 |
CQDs | Zebrafish (Danio rerio), zooplankton (Daphnia magna), and phytoplankton (Scenedesmus obliquus) | Direct exposure | 0–200 mg/L |
96 h (zebrafish) 48 h (D. magna and S. obliquus) |
Results indicated trophic level-specific toxicity of CQDs, and the oxidative stress and pH alterations served as potential mechanisms underlying the toxicity of CQDs on S. obliquus, which may separately or jointly disturb the physiological processes in algal cells and affect growth | Yao et al. 2018 |
PEG-coated Ag2Se | Male CD-1 (ICR) mice | IV injection | 8 μmol/kg body weight | 28 days | Ag2Se QDs-PEG only showed slight toxicity to the liver at day 28 post-exposure | Tang et al. 2016 |