Figure 3.

CD56^dimNKG2A⁺KIR⁻ NK cells proliferate less in PTLD compared to those in IM patients shortly after diagnosis. (A) Flow cytometric gating of the frequency of Ki-67 expressing cells of CD56^dimNKG2A⁺KIR⁻ and CD56^dimNKG2A⁻KIR⁺ NK cell subsets with isotype control antibody or anti-human Ki67 antibody in 1 representative IM patient. Frequency change of Ki-67 expressing cells of (B) CD56^dimNKG2A⁺KIR⁻ NK cell subset and (C) CD56^dimNKG2A⁻KIR⁺ NK cell subsets in 17 IM and 15 PTLD patients at diagnosis and 1 month post-diagnosis, respectively. Median ± interquartile range is shown. Mann-Whitney tests were applied to compare different groups. ns, p > 0.05 and *p ≤ 0.05.