Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jun 17;11:1188. doi: 10.3389/fimmu.2020.01188

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Hofer, Ramberger, Gredler, Pescoller, Rostásy, Sospedra, Hegen, Berger, Lutterotti and Reindl.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

CD4⁺ T-cell reactivity to MOG peptides in participants with AQP4-Ab (n = 5), MOG-Ab (n = 10), MS (n = 8) and HC (n = 14). (A) Percentage of participants with positive CD4⁺ T-cell proliferation (CDI ≥ 3) after challenging with respective MOG peptides and the positive control TTX. Percentage of participants with positive secretion (SI ≥ 3) of GM-CSF (B), IFN-γ (C) and IL-6 (D) after challenging with respective MOG peptides and the positive control TTX. The 95% confidence intervals are indicated by the error bars. AQP4-Ab, aquaporin-4 antibody positive; CDI, cell division index; GM-CSF, granulocyte-macrophage-colony-stimulating factor; HC, healthy controls; IFN, interferon; IL, interleukin; MOG-Ab, myelin oligodendrocyte glycoprotein antibody positive; MS, multiple sclerosis; SI, stimulation index; TTX, tetanus toxoid.