Table 1.
Animal characteristics
| B6 | MIN | |
|---|---|---|
| No. of mice | 11 | 10 |
| BW, g | ||
| Peak | 27.5 ± 0.3 | 25.5 ± 0.4 |
| Pre | 27.6 ± 0.3 | 23.5 ± 0.5*† |
| Post | 27.8 ± 0.3 | 22.6 ± 0.5*†‡ |
| % Change, peak to postpeak | 1.1 ± 0.5 | −11.4 ± 1.5* |
| Tibialis anterior, mg | ||
| Control | 47.7 ± 1.0 | 32.6 ± 1.6# |
| ECC | 49.8 ± 1.0§ | 36.0 ± 1.5#§ |
| Epididymal fat, mg | 309 ± 27 | 69 ± 21* |
| Spleen, mg | 72 ± 2 | 593 ± 28* |
| Testes, mg | 198 ± 3 | 136 ± 12* |
| LABC, mg | 89 ± 2 | 46 ± 5* |
| Seminal vesicle, mg | 234 ± 18 | 53 ± 7* |
| Tumor number | 0 ± 0 | 68 ± 9* |
| Food intake, g food/g BW | 0.11 ± 0.003 | 0.12 ± 0.003 |
| Tibia length, mm | 16.9 ± 0.1 | 16.8 ± 0.1 |
Data are means ± SE. BW, body weight; B6, C57BL/6 mice; ECC, eccentric contraction; LABC, levator ani-bulbocavernosus muscle; MIN, ApcMin/+ mice. A 2-way repeated-measures ANOVA with Student–Newman–Keuls post hoc methods was performed when appropriate. Student’s t test was performed when appropriate. Statistical significance was set at P < 0.05.
Significantly different from B6.
Significantly different from peak BW.
Significantly different from pre BW.
Main effect of MIN.
Main effect of ECC.