Table 1.

Quantification of mitochondria and vasculature

Groups					Mean Vessel Diameter, μm
	n	Mitochondrial Area, pixel	Vessel Area, pixel	Mitochondrial-to-Vessel Ratio		n
1×
0 wk1×	27	5,966 (SD 4,800)	30,493 (SD 14,757)	0.182 (SD 0.067)*	5.00 (SD 0.2)	9
2 wk1×	27	4,830 (SD 5,036)	31,416 (SD 23,943)	0.138 (SD 0.048)	4.95 (SD 0.2)	9
4 wk1×	27	4,108 (SD 3,619)	27,650 (SD 16,423)	0.144 (SD 0.057)	4.84 (SD 0.2)	9
12 wk1×	24	6,005 (SD 5,812)	41,675 (SD 27,219)	0.138 (SD 0.073)	5.00 (SD 0.3)	8
3×
0 wk3×	62	5,476 (SD 2,456)‡	33,583 (SD 13,160)	0.171 (SD 0.062)†	4.46 (SD 3.6)	62
2 wk3×	60	3,917 (SD 1,773)	33,811 (SD 15,691)	0.123 (SD 0.048)	4.58 (SD 3.9)	60
4 wk3×	62	3,353 (SD 2,123)	30,210 (SD 15,793)§	0.115 (SD 0.043)	3.84 (SD 1.1)	62
12 wk3×	45	3,447 (SD 1,309)	36,836 (SD 17,117)	0.107 (SD 0.048)	4.14 (SD 2.4)	45

Values are means (SD). Area measurements for mitochondria and vessels area provided in pixel. Total image area (A) at 1× and 3× is equal to 262,144 pixel, and A_1× = 138,736 μm² and A_3× = 15,813 μm². Mitochondrial-to-vessel ratio was calculated based on the area values expressed in pixel.

^*P < 0.05, mitochondrial-to-vessel ratio 0 wk_1x vs. 12 wk_1x;

^†P < 0.05, mitochondrial-to-vessel ratio 0 wk_3x vs. 2–12 wk_3x;

^‡P < 0.05, mitochondrial area 0 wk_3x vs. 2–12 wk_3x; and

^§P = 0.0484. Vessel area 4 wk_3x vs. 12 wk_3x.