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Homozygous Ift81 knockout males were infertile
| Genotype | Fertility | Litter Size | Testis/Body Wt, mg/g | Sperm Counts, 104/mL |
|---|---|---|---|---|
| Control, n = 8 | 8/8 | 6.40 ± 0.76 | 7.40 ± 0.45 | 450.13 ± 42.34 |
| KO, n = 5 | 0/5 | 0 | 6.95 ± 0.72 | 15.21 ± 1.95 |
Values are means ± SD. To test fertility, 3- to 4-mo-old control and conditional intraflagellar transport 81 (Ift81) knockout (KO) mice were bred to 3- to 4-mo-old wild-type females for ≥2 mo. Litter size was recorded for each mating.
