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. 2020 Apr 29;318(6):C1238–C1251. doi: 10.1152/ajpcell.00575.2019

Table 2.

ktr and VO at maximal and submaximal Ca2+ levels

Young Old P Value Men Women P Value
Slow MHC I
n (N) 83 (15) 155 (19) 135 (20) 103 (14)
ktr pCa 4.5, /s 2.12 ± 0.37 2.09 ± 0.41 0.564 2.06 ± 0.41 2.15 ± 0.38 0.193
ktr pCa50, /s 0.58 ± 0.17 0.55 ± 0.15 0.793 0.57 ± 0.16 0.56 ± 0.15 0.862
% Change −72 ± 9 −73 ± 9 0.803 −72 ± 11 −74 ± 6 0.257
n (N) 73 (14) 131 (19) 116 (19) 88 (14)
VO pCa 4.5, fl/s 1.14 ± 0.31 1.07 ± 0.29 0.377 1.12 ± 0.35 1.06 ± 0.21 0.368
VO pCa50, fl/s 0.45 ± 0.18 0.38 ± 0.14 0.138 0.41 ± 0.17 0.41 ± 0.14 0.578
% Change −61 ± 9 −64 ± 8 0.240 −64 ± 9 −62 ± 8 0.516
Fast MHC IIa
n (N) 80 (17) 131 (18) 113 (20) 98 (15)
ktr pCa 4.5, /s 6.59 ± 1.35 7.04 ± 1.57 0.252 6.69 ± 1.54 7.07 ± 1.44 0.250
ktr pCa50, /s 1.60 ± 0.45 1.66 ± 0.51 0.622 1.69 ± 0.55 1.59 ± 0.40 0.199
% Change −75 ± 7 −76 ± 7 0.535 −74 ± 8 −77 ± 6 0.033
n (N) 58 (15) 91 (18) 81 (19) 68 (14)
VO pCa 4.5, fl/s 3.20 ± 1.07 3.38 ± 1.09 0.563 3.46 ± 1.11 3.13 ± 1.02 0.235
VO pCa50, fl/s 0.97 ± 0.58 0.97 ± 0.44 0.839 1.03 ± 0.55 0.89 ± 0.41 0.354
% Change −72 ± 9 −71 ± 9 0.923 −71 ± 10 −72 ± 8 0.736

Data are presented as means ± SD. The number of fibers (n) and number of subjects (N) are reported for each group and fiber type. Sexes are combined when comparing age groups, and ages are combined when comparing between sexes. ktr, rate of force development; VO, unloaded shortening velocity. Boldfaced P values highlight statistical significance at P < 0.05.