Table 1.

Expression of NMDAR subunits documented in megakaryocytic and erythroid cells.

	Megakaryocytic cells 1						Erythroid cells 2			Mature brain cortex 3
	Human				Mouse		Human			Mouse and human
	Normal		Leukemic		Normal		Normal – cultured			Normal
GluN subunit	Whole bone marrow	Isolated mature MKs	Cell lines	Patient-derived	Isolated mature MKs	Early cultured MKs	Proerythroblasts	Orthochromatic	Retics /RBC	Neurons
1	+; P	−	+/++; P	+	+	++; P	+	+	+; P	+++; P
2A	+	+	++; P	+	+	++	++; P	+	+; P	++; P
2B	−	−	−/+	+	−	−	−	−	−	++; P
2C	−	−	−/+	++	+	−	+; P	+++; P	++; P	+; P
2D	+	+	+++; P	+++	++	−	++; P	++; P	++; P	+; P
3A	−	−	+	++	−	−	+; P	+; P	+; P	−
3B	−	−	+++	++	++	−	+; P	++; P	++; P	−

¹Data generated mostly by RT-PCR, conventional and real-time (Genever et al., 1999; Hitchcock et al., 2003; Kamal et al., 2015, 2018).

²Data generated by TaqMan quantitative RT-PCR, flow cytometry and immunoblotting (Makhro et al., 2013; Hanggi et al., 2014, 2015).

³Shown by multiple techniques. The “+” symbol means expression was demonstrated; the number of “+” signs reflects the level of expression; “−” means expression was not detected. The letter “P” indicates protein expression was documented using flow cytometry or immunostaining in addition to transcript data, on which the semi-quantitative assessment was based. MK, megakaryocyte; Retics, reticulocytes; RBC, red blood cells.