TABLE 2.
Neuroticism | Extraversion | Openness | Agreeableness | Conscientiousness | |
---|---|---|---|---|---|
Self‐report | |||||
Mutation | 4.34** | −3.03 | −1.12 | −0.003 | −5.45*** |
(2.00) | (1.74) | (1.60) | (1.26) | (1.70) | |
EYO | −0.31*** | 0.01 | −0.08 | 0.10 | 0.15 |
(0.09) | (0.08) | (0.07) | (0.06) | (0.08) | |
CDR‐SB | 0.13 | −0.80 | −0.46 | 0.03 | −0.72 |
(0.47) | (0.41) | (0.38) | (0.30) | (0.40) | |
Sex | −2.58 | −1.71 | −3.49*** | −7.43*** | −3.40*** |
(1.32) | (1.15) | (1.06) | (0.83) | (1.12) | |
Education | −0.76*** | 0.10 | 0.59*** | 0.55*** | 0.63*** |
(0.23) | (0.20) | (0.18) | (0.14) | (0.20) | |
Mutation × EYO | 0.33** | −0.11 | −0.07 | 0.04 | −0.25** |
(0.13) | (0.11) | (0.10) | (0.08) | (0.11) | |
Constant | 59.19*** | 85.87*** | 79.87*** | 100.80*** | 99.64*** |
(1.60) | (1.33) | (1.26) | (1.00) | (1.39) |
Collateral source ratings | |||||
---|---|---|---|---|---|
Mutation | 6.69*** | −4.01** | −2.72 | −1.94 | −5.43*** |
(2.15) | (1.84) | (1.45) | (1.59) | (2.05) | |
EYO | −0.16 | −0.01 | −0.04 | 0.11 | 0.13 |
(0.10) | (0.08) | (0.06) | (0.07) | (0.09) | |
CDR‐SB | 1.41*** | −2.76*** | −1.46*** | −1.02*** | −3.11*** |
(0.50) | (0.43) | (0.34) | (0.37) | (0.48) | |
Sex | −5.38*** | −0.75 | −3.19*** | −2.94*** | −1.70 |
(1.43) | (1.22) | (0.97) | (1.05) | (1.36) | |
Education | −0.80*** | 0.21 | 0.77*** | 0.68*** | 0.86*** |
(0.25) | (0.21) | (0.16) | (0.19) | (0.24) | |
Mutation × EYO | 0.30** | −0.14 | −0.16 | −0.09 | −0.21 |
(0.14) | (0.12) | (0.09) | (0.10) | (0.13) | |
Constant | 58.55*** | 85.89*** | 78.56*** | 100.76*** | 101.17*** |
(1.67) | (1.40) | (1.10) | (1.32) | (1.65) |
Note: **P < .05; ***P < .01.
Abbreviations: CDR‐SB, Clinical Dementia Rating‐Sum of Boxes; EYO, estimated years to onset; SE, standard error