Figure 2.

Schematic representation of Gemin5 domains and functions. The amino acids flanking each domain of the protein, as well as the p85 product resulting from the L protease cleavage, are indicated at the top. Known RNA targets of the different domains are depicted in relation to the observed function of the Gemin5 protein. The tetratricopeptide repeat (TPR)-like domain mediates the dimerization of the protein. See text for details on the impact of the indicated domains on the diverse functional roles of the protein.