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. 2020 May 28;21(11):3852. doi: 10.3390/ijms21113852

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of different classification and sorting combinations on CoM candidate set sizes. Each solid line represents the number of valid CoM candidates for an RNA pair with a rank not higher than the known CoM from literature (designated as CoM*; colors differentiate between the single CoMs). The left-most data points represent the overall numbers of CoM candidates. The black dotted line provides the average over all RNA pairs. The red dotted line depicts the number of RNA pairs for which the known CoM* does not fulfill the constraints.