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. 2020 May 29;21(11):3867. doi: 10.3390/ijms21113867

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Muscle peroxisome proliferator-activated receptor gamma coactivator 1-α (PGC-1α) and plasma brain-derived neurotrophic factor (BDNF) levels analyzed by Western blot and ELISA, respectively. (a) Increased PGC-1α expressions were observed in the Cex and Dex groups compared to the C and D groups. (b) Plasma BDNF levels were significantly decreased in the D group, whereas exercise normalized these reductions in the Dex group. C: control; D: DEHP exposure; Cex: exercised control; Dex: exercised DEHP exposure. Data are presented in mean ± SEM (n = 10 in each group). *: p < 0.05, ***: p < 0.005, ****: p < 0.001.