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Anticoagulant activity of different aptamers expressed as the ratio between the coagulation rate in the only presence of the protein and in the presence of both thrombin and each oligonucleotide. The values are reported as the average of at least three independent measurements with their standard deviation.
| Anticoagulant Activity | |
|---|---|
| NU172 | 900 ± 200 |
| NU | 2 ± 0.4 |
| cycNU172-EG2 | 10 ± 2 |
| cycNU172-EG3 | 30 ± 6 |
| cycNU172-Ph | 200 ± 50 |
| cycNU172-Pro | 50 ± 7 |
