DAPI |
4′,6-diamidino-2-phenylindole |
AOPs |
adverse outcome pathways |
AO |
adverse outcome |
AR |
androgen receptors |
BrdU |
bromodeoxyuridine |
CNS |
central nervous system |
DNT |
developmental neurotoxicity |
DCX |
doublecortin |
EDCs |
endocrine-disrupting chemicals |
ER |
estrogen receptors |
GFAP |
glial fibrillary acidic protein |
HI |
hazard index |
HQ |
hazard quotients |
HCIA |
high content image acquisition |
hiPSCs |
human induced pluripotent stem cells |
KE |
key event |
LDH |
lactate dehydrogenase |
LXRs |
liver X/oxysterols receptors |
MPO |
medial preoptic area medial preoptic area |
MEA |
microelectrode arrays |
MAP2 |
microtubule-associated protein 2 |
MIE |
molecular initiating event |
MBP |
myelin basic protein |
NPCs |
neural progenitor cells |
OECD |
Organisation for Economic Co-operation and Development |
PPARs |
peroxisome proliferator-activated receptors |
PBTK |
physiologically based toxicokinetic |
POD |
point of departure |
PCBs |
polychlorinated biphenyls |
PBDEs |
polybrominated diphenyl ethers |
PSD95 |
postsynaptic density protein 95 |
PR |
progesterone receptor |
PGE2 |
prostaglandin E2 |
QSAR |
quantitative structure–activity relationship |
RAR |
retinoic acid receptors |
RXR |
retinoic X receptors |
SMRI |
similar mixture risk indicator |
SOPs |
standard operating procedures |
SVZ |
subventricular zone |
TGs |
test guidelines |
TH |
thyroid hormone |
TR |
thyroid receptors |
VDR |
vitamin D3 receptor |