Table 4.
Minimal inhibitory concentrations and hemolitic activity of coordination compounds 32–41 [64].
| Compound | S. Aureus | S. Aureus | E. Jaecalis | E. Coli | P. Aeruginosa | % Lysis Rbcs |
|---|---|---|---|---|---|---|
| MRSA252 | MSSA209 | NCTC775 | NCTC86 | ATCC27853 | +/− (SD) | |
| 32 | 32 | 32 | 32 | 64 | >128 | 2.0 (0.4) |
| 33 | 32 | 32 | 8 | 64 | >128 | 2.1 (0.1) |
| 34 | 88 | 16 | 4 | 32 | >128 | 2.6 (0.3) |
| 35 | 8 | 4 | 2 | 32 | >128 | 2.2 (0.7) |
| 36 | 4 | 4 | 4 | 16 | >128 | 2.5 (0.3) |
| 37 | 4 | 4 | 4 | 16 | >128 | 2.0 (0.3) |
| 38 | 2 | 2 | 2 | 16 | >128 | 3.1 (0.2) |
| 39 | 2 | 2 | 2 | 16 | >128 | ND |
| 40 | 128 | 32 | 4 | 16 | >128 | ND |
| 41 | 64 | 64 | 16 | 32 | >128 | ND |
| Vancomycin | 0.25 | 0.5 | 0.5 | ND | ND | 2.6(0.2) |
| Chloramphenicol | IG | 16 | 4 | 2 | 128 | ND |
| CuCl2*2H2O | >128 | >128 | >128 | >128 | >128 | 2.0 (0.3) |