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MIA has no effect on activation of astrocytes in brain cortex of adolescent male rats. Immuno-histochemical analysis of somatosensory cortex illustrating astrocytes (GFAP- red) in control and MIA-exposed groups. Co-expression of activation markers, (a) IL-1β (green) and (b) arginase-1 (green), with GFAP-positive cells has not been observed. The nuclei were counterstained with DAPI (blue). Scale bar = 50 μm.
