Figure 3.
Correlations between the cellular NAD(P)H:XTT reductase activity and the OGDHC partition into the holo- and apo-OGDHC. The data for eight experimental groups including A549wt and A549p21- cells under different thiamine/ThDP saturation are used. All datasets successfully passed the D’Agostino & Pearson omnibus normality test. Linear regressions of Pearson’s correlation are presented, with their correlation coefficients (r) and p-values (p) for statistical significance given on the graphs. (A) Correlation between the NAD(P)H:XTT reductase activity and the holo-OGDHC level. (B) Correlation between the NAD(P)H:XTT reductase activity and the apo-OGDHC level. (C) Correlation between the NAD(P)H:XTT reductase activity and ratio (in %) of holo-OGDHC to total OGDHC.