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Inverse relationship between the OGDHC activity and glutathione level, assayed in the Vero and A549wt cell lines under control conditions. The data of at least three independent experiments are presented as means ± SEM.
| Cell Line | Vero | A549wt |
|---|---|---|
| GSH, nmol/mg | 1.2 ± 0.1 | 37.7 ± 2.6 |
| Activity, nmol/(min∙mg) | ||
| total OGDHC | 1.76 ± 0.30 | 0.33 ± 0.08 |
| holo-OGDHC | 1.68 ± 0.22 | 0.07 ± 0.03 |
| apo-OGDHC | 0.07 ± 0.30 | 0.25 ± 0.08 |
