Table 1.
Microbial antigens recognized by iNKT cells (adapted from [9]).
| Microorganism | Pathogenicity | Antigen |
|---|---|---|
| Arthrobacter | Commensal, opportunist | M-AcM-MAG |
| Aspergillus fumigatus and Aspergillus niger | Opportunists | Asperamide B |
| Bacteroides fragilis | Commensal, opportunist | α-GalCer (Bf) |
| Bacteroides vulgatus | Commensal, opportunist | α-GalCer |
| Borrelia burgdorferi | Pathogen | BbGL-II (1,2-di-O-acyl- 3-O-a Dgalactopyranosyl-sn-glycerol, 6) |
| Candida albicans | Commensal, opportunist | ChAcMan |
| Ehrlichia muris | Pathogen in rodents only | Not defined |
| Entamoeba histolytica | Opportunist | Lipopeptidophosphoglycan (EhLPPG) |
| Helicobacter pylori | Commensal, opportunist | Cholestoryl-a-glucosides, especially monoacyl a-CPG |
| Lactobacillus casei | Commensal | Glc-DAG |
| Leishmania donovani | Opportunist | Lipophosphoglycan (LPG) |
| Mycobacterium tuberculosis | Pathogen | Phosphatidylinositol mannoside (PIM) |
| Prevotella copri | Commensal | α-GalCer |
| Rothia dentocariosa | Commensal, opportunist | M-AcM-MAG |
| Saccharopolyspora | Environmental, opportunist | M-AcM-MAG |
| Sphingomonas paucimobilis | Commensal, opportunist | a-glucuronosyl ceramide (GSL-1/ aGlcUCer) |
| Sphingomonas yanoikuyae | Environmental, commensal, opportunist | a-galacturonosyl-ceramides |
| Sphingomonas wittichi | No pathogenicity reported | a-galacturonosyl-ceramides |
| Streptococcus pneumoniae and Group B Streptococcus | Commensal, opportunists | SPN-Glc-DAG, SPN-Gal-Glc-DAG |