Table 2.
Univariable and multivariable logistic regression analyses for unfavourable outcomes
| Parameter | Univariable analysis | Multivariable analysis | ||||
| OR | 95% CI* | P value | OR | 95% CI* | P value | |
| Age | 1.03 | 1.01 to 1.04 | <0.0001 | 1.02 | 1.00 to 1.05 | 0.037 |
| Male gender | 0.63 | 0.45 to 0.90 | 0.011 | 0.72 | 0.40 to 1.28 | 0.259 |
| Hypertension | 0.92 | 0.64 to 1.33 | 0.659 | – | ||
| Atrial fibrillation | 2.19 | 1.35 to 3.55 | 0.001 | 1.99 | 0.80 to 5.06 | 0.151 |
| Hypercholesterolemia | 0.89 | 0.62 to 1.28 | 0.530 | – | ||
| Coronary heart disease | 1.89 | 1.16 to 3.08 | 0.011 | 1.03 | 0.47 to 2.28 | 0.940 |
| Previous TIA or stroke | 1.29 | 0.82 to 2.03 | 0.280 | – | ||
| Active Smoking | 1.08 | 0.76 to 1.53 | 0.664 | – | ||
| BMI | 0.97 | 0.912 to 1.02 | 0.226 | – | ||
| Systolic blood pressure | 1.00 | 1.00 to 1.01 | 0.966 | – | ||
| Diastolic blood pressure | 1.00 | 1.00 to 1.01 | 0.875 | – | ||
| Reperfusion therapy | 0.90 | 0.43 to 1.89 | 0.785 | – | ||
| NIHSS score at admission | 1.58 | 1.46 to 1.70 | <0.0001 | 1.42 | 1.31 to 1.55 | <0.0001 |
| Large-vessel occlusive† | 1.12 | 0.38 to 3.35 | 0.839 | – | ||
| Small-vessel occlusive† | 0.07 | 0.02 to 0.19 | <0.0001 | 0.24 | 0.06 to 0.93 | 0.039 |
| Cardioembolic† | 1.25 | 0.37 to 4.72 | 0.717 | – | ||
| HbA1c (%) | 1.11 | 1.01 to 1.23 | 0.038 | 0.84 | 0.71 to 1.01 | 0.056 |
| FBG | 1.38 | 1.29 to 1.48 | <0.0001 | 1.25 | 1.14 to 1.37 | <0.0001 |
*Note that the OR corresponds to a unit increase in the explanatory variable.
†Other and unknown ischaemic stroke subtype as the reference.
BMI, body mass index; FBG, fasting blood glucose; HbA1c, glycated haemoglobin; NIHSS, National Institutes of Health Stroke Scale; TIA, transient ischaemic attack.