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. 2020 Jun 23;8(1):e000842. doi: 10.1136/jitc-2020-000842

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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Schemata of Checkmate-064, Checkmate-066 and Checkmate-067 clinical trials. Stage of disease, number of enrolled and treated patients, study endpoints, and survival database information are shown for the phase II randomized Checkmate-064, and phase III randomized Checkmate-066 and Checkmate-067 trials. ^*Switch in treatment at week 13. AJCC, American Joint Committee on Cancer; HRQOL, health-related quality of life; IPI, ipilimumab; M, metastases; NIVO, nivolumab; ORR, objective response rate; OS, overall survival; PD, pharmacodynamics; PFS, progression-free survival; PK, pharmacokinetics; R, randomized; TRAE, treatment-related adverse event.