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. 2020 Jun 23;8(1):e000328. doi: 10.1136/jitc-2019-000328

Figure 6.

Figure 6

Temporal changes measured by conventional DWI and IMPULSED after either control IgG-treatment or dual ICB treatment in MC38 tumor models, including conventional ADC and IMPULSED-derived parameters (d, vin, Din, and Dex). *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001, as measured by two-way repeated-measures analysis of variance with a Tukey post-hoc test. ADC, Apparent Diffusion Coefficient; DWI, diffusion weighted imaging; ICB, immune-checkpoint blockade; IMPULSED, Microstructural Parameters Using Limited Spectrally Edited Diffusion.