Table 1.

Compounds 832, 869, and 145 as PDE inhibitors.

Compound	PDE-IC50 [µM]
	1A	1B	1C	3A	3B	4A	4B	4D	5A	7A	8A
832	7.24	0.04	89.18	0.125	0.42	4.75	4.4 3	n.a.	n.a.	10.5 3	n.a.
869	n.a.	n.a.	172.18	n.a.	156.70	58.05	n.a.	n.a.	n.a.	n.a.	n.a.
145	n.a.	2.69 1	48.52	0.18 1	2.05	1.59	5.43 2	13.85 1	103.88 1	5.07 2	73.18
IBMX	0.11	35.70 1	12.52	0.71 1	0.31	16.39	46.60 4	81.94	45.09 1	77.70 4	n.a.

Values published previously: ¹ [19]; ² [20]; ³ [21]; ⁴ [22]; n.a.—not active