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. 2020 Apr 29;60(6):3030–3042. doi: 10.1021/acs.jcim.0c00190

Table 1. Summary of Serine Proteases Which Were Considered in This Studya.

protease pH activity range experimental pKa values
elastase 7–7.5 ND
trypsin 7–8 ND
granzyme B 7–8 ND
chymotrypsin 8–9 7.5
a

Activity ranges reported in literature and available experimental pKa values are given.