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. 2020 Feb 12;100(7):974–985. doi: 10.1038/s41374-020-0402-y

Fig. 6. DNA methylation analysis of heart tissues for Dnmt1 knockout in response to ADR treatment.

Fig. 6

a Differentially methylated regions (DMRs) for CG DMR gene region distribution in both KO-saline vs. WT-saline and KO-ADR vs. WT-ADR. b Average of CpG methylation changes between KO-saline and WT-saline groups. c Average of CpG methylation changes between KO-ADR and WT-ADR groups. d Correlation analysis between transcriptional level and methylation state for gene with significant changes in transcriptome analysis. e Six signaling pathways from KEGG pathway enrichment analysis in both WT-ADR vs. WT-Saline and KO-ADR vs. KO-saline.