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Blocking of the JAK2/STAT3 pathway by JAK2 inhibitor, AG490. (a) Weight of the right median lobe of the liver to body weight (RML/BW) ratio. (b) Messenger RNA expression of proliferating cell nuclear antigen (PCNA). (c) PCNA labeling index. Samples were taken on day 1 after administration of Janus kinase (JAK) 2 inhibitor AG490; values are expressed as mean ± SD; n = 6 for each group; * p < 0.05.
