Figure 2.

a) The representative immunofluorescence images of P. aeruginosa biofilm with different treatments for 2 h and then stained by hypoxyprobe; b) Quantification of fluorescence intensity in different groups shown in (a); The results of standard plate counting assay of c) P. aeruginosa biofilm treated with aztreonam (AZT, a representative antibiotic of penicillin) and lip@PFH@O₂ with different oxygen concentrations, d) P. aeruginosa biofilm treated with ceftazidime (TAZ, a representative antibiotic of cephalosporin) and lip@PFH@O₂ with different oxygen concentrations, and e) P. aeruginosa biofilm treated with piperacillin‐tazobactam (P/T, a kind of representative mixed antibiotics) and lip@PFH@O₂ with different oxygen concentrations; f) Minimum bactericidal concentration of three kinds of antibiotics (aztreonam, AZT; ceftazidime, TAZ; piperacillin‐tazobactam, P/T) for P. aeruginosa biofilm.